PANTHER Classification System

"The PANTHER (Protein ANalysis THrough Evolutionary Relationships) Classification System was designed to classify proteins (and their genes) in order to facilitate high-throughput analysis. Proteins have been classified according to: Family and subfamily: families are groups of evolutionarily related proteins; subfamilies are related proteins that also have the same function. Molecular function: the function of the protein by itself or with directly interacting proteins at a biochemical level, e.g. a protein kinase. Biological process: the function of the protein in the context of a larger network of proteins that interact to accomplish a process at the level of the cell or organism, e.g. mitosis. Pathway: similar to biological process, but a pathway also explicitly specifies the relationships between the interacting molecules. (...) Version 8.1 (release date June 1, 2013) contains 7729 protein families, divided into 68,992 functionally distinct protein subfamilies."