PANTHER Classification System

English Abstract: 

"The PANTHER (Protein ANalysis THrough Evolutionary Relationships) Classification System was designed to classify proteins (and their genes) in order to facilitate high-throughput analysis. Proteins have been classified according to: Family and subfamily: families are groups of evolutionarily related proteins; subfamilies are related proteins that also have the same function. Molecular function: the function of the protein by itself or with directly interacting proteins at a biochemical level, e.g. a protein kinase. Biological process: the function of the protein in the context of a larger network of proteins that interact to accomplish a process at the level of the cell or organism, e.g. mitosis. Pathway: similar to biological process, but a pathway also explicitly specifies the relationships between the interacting molecules. (...) Version 8.1 (release date June 1, 2013) contains 7729 protein families, divided into 68,992 functionally distinct protein subfamilies."

Alternative Title: 
Protein ANalysis THrough Evolutionary Relationships Classification System
English Title: 
PANTHER Classification System
Author: 
Paul D. Thomas
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Address: 
Health Sciences Campus, University of Southern California, Los Angeles, CA, 90089-9034, United States