genetics

Human Phenotype Ontology

"The Human Phenotype Ontology (HPO) aims to provide a standardized vocabulary of phenotypic abnormalities encountered in human disease. Each term in the HPO describes a phenotypic abnormality, such as atrial septal defect. The HPO is currently being developed using the medical literature, Orphanet, DECIPHER, and OMIM. HPO currently contains approximately 11,000 terms and over 115,000 annotations to hereditary diseases. The HPO also provides a large set of HPO annotations to approximately 4000 common diseases.

Genomic Clinical Decision Support Ontology

"The Genomic Clinical Decision Support (Genomic CDS) project aims to create and maintain an integrated, ontology-based knowledge base of clinically relevant pharmacogenomic information. This knowledge base is used to implement clinical decision support algorithms for improving quality of care, e.g., for providing drug dosage recommendations and comparisons of the efficacy of different treatment options."

Gene Ontology

"The Gene Ontology project is a major bioinformatics initiative with the aim of standardizing the representation of gene and gene product attributes across species and databases. The project provides a controlled vocabulary of terms for describing gene product characteristics and gene product annotation data from GO Consortium members, as well as tools to access and process this data."

Ontology for Genetic Interval

"Using realistic ontology BFO as its top ontology's framwork, OGI formalized the genomic element by defining an upper class 'genetic interval'. The definition of 'genetic interval' is "the spatial continuous physical entity which contains ordered genomic sets(DNA, RNA, Allele, Marker,etc.) between and including two points (Nucleic Acid Base Residue) that have a liner primary sequence sturcture. It is either a proper part of an chromosome or a RNA molecule or an artificial genetic interval."

Mobile Genetic Element Ontology

"MeGO is a Gene Ontology under construction dedicated to the functions of mobile genetic elements. The terms defined in MeGO are used to annotate phage and plasmid protein families in ACLAME.
Please note that some terms in the ontology are there transiently as markers or awaiting future incorporation in the sequence ontology (SO). The phage ontology PhiGO has now been incorporated in MeGO and can thus be accessed in MeGO version 1.0 and up."

A Classification of Mobile Genetic Elements

"ACLAME is a database dedicated to the collection and classification of mobile genetic elements (MGEs) from various sources, comprising all known phage genomes, plasmids and transposons. In addition to provide information on the full genomes and genetic entities, it aims at building a comprehensive classification of the functional modules of MGE's at the protein, gene, and higher levels. There are 122154 proteins found in 2326 MGEs. Total number of host is 811 (Version 0.4)."

"ACLAME is a database dedicated to the collection and classification of mobile genetic elements (MGEs) from various sources, comprising all known phage genomes, plasmids and transposons. In addition to provide information on the full genomes and genetic entities, it aims at building a comprehensive classification of the functional modules of MGE's at the protein, gene, and higher levels. There are 122154 proteins found in 2326 MGEs. Total number of host is 811 (Version 0.4)."

National Center for Biotechnology Information Taxonomy

"The NCBI Taxonomy database is a curated set of names and classifications for all of the organisms that are represented in GenBank. When new sequences are submitted to GenBank, the submission is checked for new organism names, which are then classified and added to the Taxonomy database. As of April 2003, there were 176,890 total taxa represented.

"The NCBI Taxonomy database is a curated set of names and classifications for all of the organisms that are represented in GenBank. When new sequences are submitted to GenBank, the submission is checked for new organism names, which are then classified and added to the Taxonomy database. As of April 2003, there were 176,890 total taxa represented.