enzyme

UniProtKB Keywords

"UniProtKB Keywords constitute a controlled vocabulary with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest. Keywords are classified in 10 categories: Biological process, Cellular component, Coding sequence diversity, Developmental stage, Disease, Domain, Ligand, Molecular function, Post-translational modification, Technical term. An entry often contains several keywords. Inside a category, the keywords are stored in alphabetical order.

"UniProtKB Keywords constitute a controlled vocabulary with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest. Keywords are classified in 10 categories: Biological process, Cellular component, Coding sequence diversity, Developmental stage, Disease, Domain, Ligand, Molecular function, Post-translational modification, Technical term. An entry often contains several keywords. Inside a category, the keywords are stored in alphabetical order.

PANTHER Classification System

"The PANTHER (Protein ANalysis THrough Evolutionary Relationships) Classification System was designed to classify proteins (and their genes) in order to facilitate high-throughput analysis. Proteins have been classified according to: Family and subfamily: families are groups of evolutionarily related proteins; subfamilies are related proteins that also have the same function. Molecular function: the function of the protein by itself or with directly interacting proteins at a biochemical level, e.g. a protein kinase.

Enzyme Nomenclature

"By the late 1950's it had become evident that the nomenclature of enzymology, in the absence of any guiding authority, in a period when the number of known enzymes was increasing rapidly, was getting out of hand. The naming of enzymes by individual workers had proved far from satisfactory in practice. In many cases the same enzymes became known by several different names, while conversely the same name was sometimes given to different enzymes.

"By the late 1950's it had become evident that the nomenclature of enzymology, in the absence of any guiding authority, in a period when the number of known enzymes was increasing rapidly, was getting out of hand. The naming of enzymes by individual workers had proved far from satisfactory in practice. In many cases the same enzymes became known by several different names, while conversely the same name was sometimes given to different enzymes.

Multiple Alignment Ontology

"The goal of the MAO project is to develop a controlled, structured vocabulary, that will provide a common language not only for the construction of multiple alignments, but also for the numerous applications that exploit the information available in an integrated, global multiple alignment of a protein family. An important issue in the development of MAO is the interoperability with existing information sources, in order to maximise its’ applicability and utility.

Glycomics Ontology

"The Glycomics Ontology (GlycO) focuses on the glycoproteomics domain to model the structure and functions of glycans and glycoconjugates, the enzymes involved in their biosynthesis and modification, and the metabolic pathways in which they participate. GlycO is intended to provide both a schema and a sufficiently large knowledge base, which will allow classification of concepts commonly encountered in the field of glycobiology in order to facilitate automated reasoning and information analysis in this domain.

Structural Classification of Proteins

"SCOP contains the domains of all PDB entries available at the time of the current release's construction. For each of these entries a coordinate file is available and can be displayed via the various graphical interfaces. The sequence of each protein chain has also been extracted. The release also contains many literature references. These are structures that have been published in sufficient detail to be classified in SCOP, but where the coordinates are not yet available from PDB.

Transporter Classification System

"The TC-DB website details a comprehensive classification system for membrane transport proteins known as the Transport Classification (TC) system. The TC system is analogous to the Enzyme Commission (EC) system for classification of enzymes, except that it incorporates both functional and phylogenetic information. Descriptions, TC numbers, and examples of over 600 families of transport proteins are provided.